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Structure paper

TitleStructure of intact human MCU supercomplex with the auxiliary MICU subunits.
Journal, issue, pagesProtein Cell, Vol. 12, Issue 3, Page 220-229, Year 2021
Publish dateJul 29, 2021
AuthorsWei Zhuo / Heng Zhou / Runyu Guo / Jingbo Yi / Laixing Zhang / Lei Yu / Yinqiang Sui / Wenwen Zeng / Peiyi Wang / Maojun Yang /
External linksProtein Cell / PubMed:32862359 / PubMed Central
MethodsEM (single particle)
Resolution3.27 - 3.6 Å
Structure data

9944

6k7x

EMDB-9944, PDB-6k7x:
Human MCU-EMRE complex
Method: EM (single particle) / Resolution: 3.27 Å

9945

6k7y

EMDB-9945, PDB-6k7y:
Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits
Method: EM (single particle) / Resolution: 3.6 Å

Chemicals

ChemComp-CDL:
CARDIOLIPIN / phospholipid*YM

ChemComp-PLX:
(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL / phospholipid*YM

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / ion channel / Mitochondrial Ca2+ uptake / MCU / MICU

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