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-Structure paper
Title | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases. |
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Journal, issue, pages | Nat Commun, Vol. 10, Page 3162-3162, Year 2019 |
Publish date | Dec 30, 2018 (structure data deposition date) |
![]() | Wang, Z. / Liu, Z. / Chen, X. / Li, J. / Yao, W. / Huang, S. / Gu, A. / Lei, Q.Y. / Mao, Y. / Wen, W. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.7 Å |
Structure data | ![]() PDB-6j1x: ![]() PDB-6j1y: ![]() PDB-6j1z: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | LIGASE / E3 ligase / close conformation / autoinhibition / Semi-open conformation / Auto-inhibition / E3 ligase semi-open conformation / Enzyme / Auto-inhibition. |