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Structure paper

TitleRetractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 4775-4783, Year 2019
Publish dateOct 17, 2018 (structure data deposition date)
AuthorsHei, Z. / Wu, S. / Liu, Z. / Wang, J. / Fang, P.
External linksJ. Biol. Chem. / PubMed:30733335
MethodsX-ray diffraction
Resolution1.882 - 2.501 Å
Structure data

PDB-6ild:
Crystal Structure of Human LysRS: P38/AIMP2 Complex II
Method: X-RAY DIFFRACTION / Resolution: 1.882 Å

PDB-6ilh:
Crystal Structure of human lysyl-tRNA synthetase L350H mutant
Method: X-RAY DIFFRACTION / Resolution: 2.501 Å

Chemicals

ChemComp-LYS:
LYSINE

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-45A:
5'-O-[(S)-hydroxy(methyl)phosphoryl]adenosine

ChemComp-HOH:
WATER

ChemComp-KAA:
5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE

Source
  • homo sapiens (human)
KeywordsLIGASE / lysyl-tRNA synthetase / LysRS / P38 / AIMP2 / multi tRNA synthetase complex sub-complex / disease related mutant

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