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Structure paper

TitleCrystal structure of the FLT3 kinase bound to a small molecule inhibitor
Journal, issue, pagesTo Be Published
Publish dateOct 16, 2018 (structure data deposition date)
AuthorsThomas, C.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6il3:
Crystal structure of the FLT3 kinase bound to a small molecule inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-A9R:
7-methoxy-6-(1-methyl-1H-pyrazol-4-yl)-3-(pyridin-2-yl)imidazo[1,2-a]pyridine

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CXS:
3-CYCLOHEXYL-1-PROPYLSULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / receptor tyrosine kinase type I inhibitor ATP binding domain DFG-in / SIGNALING PROTEIN

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