EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
ジャーナル・号・ページ	J. Biol. Chem., Vol. 293, Page 18903-18913, Year 2018
掲載日	2018年8月21日 (構造データの登録日)
著者	Del Cano-Ochoa, F. / Grande-Garcia, A. / Reverte-Lopez, M. / D'Abramo, M. / Ramon-Maiques, S.
リンク	J. Biol. Chem. / PubMed:30315107
手法	X線回折
解像度	1.14542458871 - 2.12 Å
構造データ	PDB-6hfd: Human dihydroorotase mutant F1563L apo structure 手法: X-RAY DIFFRACTION / 解像度: 1.86996804092 Å PDB-6hfe: Human dihydroorotase mutant F1563T apo structure 手法: X-RAY DIFFRACTION / 解像度: 1.47997437573 Å PDB-6hff: Human dihydroorotase mutant F1563Y apo structure 手法: X-RAY DIFFRACTION / 解像度: 1.51000106105 Å PDB-6hfh: Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.44871265165 Å PDB-6hfi: Human dihydroorotase mutant F1563A apo structure 手法: X-RAY DIFFRACTION / 解像度: 1.45994719309 Å PDB-6hfj: Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.2 Å PDB-6hfk: Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5 手法: X-RAY DIFFRACTION / 解像度: 1.45914405408 Å PDB-6hfl: Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-6hfn: Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.44965143011 Å PDB-6hfp: Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.19822864429 Å PDB-6hfq: Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.14542458871 Å PDB-6hfr: Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.29949373933 Å PDB-6hfs: Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5 手法: X-RAY DIFFRACTION / 解像度: 1.34904510922 Å PDB-6hfu: Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.39971025955 Å PDB-6hg1: Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state 手法: X-RAY DIFFRACTION / 解像度: 2.12 Å PDB-6hg2: Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to fluoroorotate 手法: X-RAY DIFFRACTION / 解像度: 1.83 Å PDB-6hg3: Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-FMT: FORMIC ACID ChemComp-HOH: WATER ChemComp-DOR: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID ChemComp-GOL: GLYCEROL ChemComp-NCD: N-CARBAMOYL-L-ASPARTATE ChemComp-FOT: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID
由来	homo sapiens (ヒト) escherichia coli (大腸菌)
キーワード	BIOSYNTHETIC PROTEIN / de novo pyrimidine biosynthesis / CAD / TIM-barrel / carboxylated lysine