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-Structure paper
Title | Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin. |
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Journal, issue, pages | J. Biol. Chem., Vol. 294, Page 5105-5120, Year 2019 |
Publish date | Dec 18, 2017 (structure data deposition date) |
![]() | Cohen, I. / Coban, M. / Shahar, A. / Sankaran, B. / Hockla, A. / Lacham, S. / Caulfield, T.R. / Radisky, E.S. / Papo, N. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.497 - 1.98 Å |
Structure data | ![]() PDB-6bx8: ![]() PDB-6har: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-EDO: ![]() ChemComp-CA: |
Source |
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![]() | HYDROLASE / Hydrolase Inhibitor / PROTEIN FIBRIL / PRSS3 / Mesotrypsin / Serine protease / Kunitz type inhibitor / APPI |