+Search query
-Structure paper
Title | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. |
---|---|
Journal, issue, pages | Science, Vol. 362, Page eaat0572-, Year 2018 |
Publish date | Jul 9, 2018 (structure data deposition date) |
![]() | Sievers, Q.L. / Petzold, G. / Bunker, R.D. / Renneville, A. / Slabicki, M. / Liddicoat, B.J. / Abdulrahman, W. / Mikkelsen, T. / Ebert, B.L. / Thoma, N.H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 3.25 - 4.25 Å |
Structure data | ![]() PDB-6h0f: ![]() PDB-6h0g: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-Y70: ![]() ChemComp-HOH: |
Source |
|
![]() | SIGNALING PROTEIN / E3 ubiquitin ligase / drug mediated protein-interaction / targeted protein degradation |