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-Structure paper
Title | Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 1385-1406, Year 2019 |
Publish date | Apr 27, 2018 (structure data deposition date) |
![]() | Granberg, K.L. / Yuan, Z.Q. / Lindmark, B. / Edman, K. / Kajanus, J. / Hogner, A. / Malmgren, M. / O'Mahony, G. / Nordqvist, A. / Lindberg, J. ...Granberg, K.L. / Yuan, Z.Q. / Lindmark, B. / Edman, K. / Kajanus, J. / Hogner, A. / Malmgren, M. / O'Mahony, G. / Nordqvist, A. / Lindberg, J. / Tangefjord, S. / Kossenjans, M. / Lofberg, C. / Branalt, J. / Liu, D. / Selmi, N. / Nikitidis, G. / Nordberg, P. / Hayen, A. / Aagaard, A. / Hansson, E. / Hermansson, M. / Ivarsson, I. / Jansson-Lofmark, R. / Karlsson, U. / Johansson, U. / William-Olsson, L. / Hartleib-Geschwindner, J. / Bamberg, K. |
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Methods | X-ray diffraction |
Resolution | 1.54 - 1.8 Å |
Structure data | ![]() PDB-6gev: ![]() PDB-6gg8: ![]() PDB-6ggg: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-EWN: ![]() ChemComp-HOH: ![]() ChemComp-MPD: ![]() ChemComp-EY8: ![]() ChemComp-CL: ![]() ChemComp-EYN: |
Source |
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![]() | TRANSCRIPTION / Mineralocorticoid receptor / nuclear hormone receptor / steroid receptor / ligand complex / peptide complex / signaling protein |