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TitleA loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Journal, issue, pagesNat Commun, Vol. 9, Page 1199-1199, Year 2018
Publish dateMar 9, 2018 (structure data deposition date)
AuthorsVigolo, M. / Chambers, M.G. / Willen, L. / Chevalley, D. / Maskos, K. / Lammens, A. / Tardivel, A. / Das, D. / Kowalczyk-Quintas, C. / Schuepbach-Mallepell, S. ...Vigolo, M. / Chambers, M.G. / Willen, L. / Chevalley, D. / Maskos, K. / Lammens, A. / Tardivel, A. / Das, D. / Kowalczyk-Quintas, C. / Schuepbach-Mallepell, S. / Smulski, C.R. / Eslami, M. / Rolink, A. / Hummler, E. / Samy, E. / Fomekong Nanfack, Y. / Mackay, F. / Liao, M. / Hess, H. / Jiang, X. / Schneider, P.
External linksNat Commun / PubMed:29572442
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-6fxn:
Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunology / B cell / cytokine / BAFF / antibody / Proteros

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