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-Structure paper
Title | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity. |
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Journal, issue, pages | Plos Biol., Vol. 17, Page e3000204-e3000204, Year 2019 |
Publish date | Jul 19, 2018 (structure data deposition date) |
Authors | Hernandez-Sanchez, W. / Huang, W. / Plucinsky, B. / Garcia-Vazquez, N. / Robinson, N.J. / Schiemann, W.P. / Berdis, A.J. / Skordalakes, E. / Taylor, D.J. |
External links | Plos Biol. / PubMed:30951520 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-6e53: |
Chemicals | ChemComp-MG: ChemComp-HUV: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / telomerase / catalytic subunit / telomerase inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex |