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TitleCorrecting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator.
Journal, issue, pagesNat Commun, Vol. 9, Page 4045-4045, Year 2018
Publish dateJul 6, 2018 (structure data deposition date)
AuthorsHwang, S. / Mruk, K. / Rahighi, S. / Raub, A.G. / Chen, C.H. / Dorn, L.E. / Horikoshi, N. / Wakatsuki, S. / Chen, J.K. / Mochly-Rosen, D.
External linksNat Commun / PubMed:30279493
MethodsX-ray diffraction
Resolution1.9 - 2.6 Å
Structure data

PDB-6e07:
Crystal structure of Canton G6PD in complex with structural NADP
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6e08:
Crystal structure of G6PD in complex with structural NADP
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / G6PD / NADP

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