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TitleGreen tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 34164-34174, Year 2011
Publish dateMay 20, 2018 (structure data deposition date)
AuthorsLi, C. / Li, M. / Chen, P. / Narayan, S. / Matschinsky, F.M. / Bennett, M.J. / Stanley, C.A. / Smith, T.J.
External linksJ. Biol. Chem. / PubMed:21813650
MethodsX-ray diffraction
Resolution3.624 Å
Structure data

PDB-6dhl:
Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ECG)
Method: X-RAY DIFFRACTION / Resolution: 3.624 Å

Chemicals

ChemComp-XEG:
(2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

Source
  • bos taurus (domestic cattle)
KeywordsOXIDOREDUCTASE / ECG / glutamate / dehydrogenase / inhibition

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