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-Structure paper
Title | Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. |
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Journal, issue, pages | Mol. Cell, Vol. 72, Page 263-274.e5, Year 2018 |
Publish date | Mar 26, 2018 (structure data deposition date) |
Authors | Mosaei, H. / Molodtsov, V. / Kepplinger, B. / Harbottle, J. / Moon, C.W. / Jeeves, R.E. / Ceccaroni, L. / Shin, Y. / Morton-Laing, S. / Marrs, E.C.L. ...Mosaei, H. / Molodtsov, V. / Kepplinger, B. / Harbottle, J. / Moon, C.W. / Jeeves, R.E. / Ceccaroni, L. / Shin, Y. / Morton-Laing, S. / Marrs, E.C.L. / Wills, C. / Clegg, W. / Yuzenkova, Y. / Perry, J.D. / Bacon, J. / Errington, J. / Allenby, N.E.E. / Hall, M.J. / Murakami, K.S. / Zenkin, N. |
External links | Mol. Cell / PubMed:30244835 |
Methods | X-ray diffraction |
Resolution | 2.994 - 4.104 Å |
Structure data | PDB-6cuu: PDB-6cux: |
Chemicals | ChemComp-KNG: ChemComp-ZN: ChemComp-MG: |
Source |
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Keywords | transcription/dna/antibiotic / RNA polymerase / Kanglemycin A / transcription inhibitor / TRANSCRIPTION / transcription-dna-antibiotic complex / transcription/antibiotic / Bacterial RNA polymerase / transcription-transcription inhibitor complex / transcription-antibiotic complex |