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TitleCrystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an ??-ketoglutarate adduct
Journal, issue, pagesto be published
Publish dateDec 29, 2017 (structure data deposition date)
AuthorsDranow, D.M. / Mayclin, S.J. / Lorimer, D.D. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-6c0e:
Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-EE1:
(3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid

ChemComp-GLY:
GLYCINE

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • legionella pneumophila subsp. pneumophila str. philadelphia 1 (bacteria)
KeywordsOXIDOREDUCTASE / SSGCID / Isocitrate dehydrogenase / 2-oxoglutarate / ketoglutarate / NADPH / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease

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