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TitleStructural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Journal, issue, pagesCell, Vol. 171, Page 1638-1648.e7, Year 2017
Publish dateOct 24, 2017 (structure data deposition date)
AuthorsSeegar, T.C.M. / Killingsworth, L.B. / Saha, N. / Meyer, P.A. / Patra, D. / Zimmerman, B. / Janes, P.W. / Rubinstein, E. / Nikolov, D.B. / Skiniotis, G. ...Seegar, T.C.M. / Killingsworth, L.B. / Saha, N. / Meyer, P.A. / Patra, D. / Zimmerman, B. / Janes, P.W. / Rubinstein, E. / Nikolov, D.B. / Skiniotis, G. / Kruse, A.C. / Blacklow, S.C.
External linksCell / PubMed:29224781
MethodsX-ray diffraction
Resolution2.8 - 3.1 Å
Structure data

PDB-6bdz:
ADAM10 Extracellular Domain Bound by the 11G2 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6be6:
ADAM10 Extracellular Domain
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CA:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / ADAM10

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