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Title | Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 9205-9217, Year 2018 |
Publish date | May 8, 2018 (structure data deposition date) |
![]() | Aida, J. / Fushimi, M. / Kusumoto, T. / Sugiyama, H. / Arimura, N. / Ikeda, S. / Sasaki, M. / Sogabe, S. / Aoyama, K. / Koike, T. |
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Methods | X-ray diffraction |
Resolution | 1.35 Å |
Structure data | ![]() PDB-5zun: |
Chemicals | ![]() ChemComp-9JX: ![]() ChemComp-PG4: ![]() ChemComp-EDO: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/INHIBITOR / MONOACYLGLYCEROL LIPASE / HYDROLASE-INHIBITOR complex |