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-Structure paper
Title | MEK drives BRAF activation through allosteric control of KSR proteins. |
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Journal, issue, pages | Nature, Vol. 554, Page 549-553, Year 2018 |
Publish date | May 10, 2017 (structure data deposition date) |
![]() | Lavoie, H. / Sahmi, M. / Maisonneuve, P. / Marullo, S.A. / Thevakumaran, N. / Jin, T. / Kurinov, I. / Sicheri, F. / Therrien, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.749 - 2.102 Å |
Structure data | ![]() PDB-5vr3: ![]() PDB-5vyk: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-GOL: |
Source |
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![]() | TRANSFERASE / BRAF / SIGNALING PROTEIN / KSR1 / BRS / CC-SAM / Complex / Kinase / Pseudokinase / Signaling. |