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-Structure paper
Title | Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 13, Page 850-857, Year 2017 |
Publish date | Mar 21, 2017 (structure data deposition date) |
![]() | Scott, D.C. / Hammill, J.T. / Min, J. / Rhee, D.Y. / Connelly, M. / Sviderskiy, V.O. / Bhasin, D. / Chen, Y. / Ong, S.S. / Chai, S.C. ...Scott, D.C. / Hammill, J.T. / Min, J. / Rhee, D.Y. / Connelly, M. / Sviderskiy, V.O. / Bhasin, D. / Chen, Y. / Ong, S.S. / Chai, S.C. / Goktug, A.N. / Huang, G. / Monda, J.K. / Low, J. / Kim, H.S. / Paulo, J.A. / Cannon, J.R. / Shelat, A.A. / Chen, T. / Kelsall, I.R. / Alpi, A.F. / Pagala, V. / Wang, X. / Peng, J. / Singh, B. / Harper, J.W. / Schulman, B.A. / Guy, R.K. |
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Methods | X-ray diffraction |
Resolution | 1.374 - 2.002 Å |
Structure data | ![]() PDB-5v83: ![]() PDB-5v86: ![]() PDB-5v88: ![]() PDB-5v89: |
Chemicals | ![]() ChemComp-8Z7: ![]() ChemComp-HOH: ![]() ChemComp-8ZA: ![]() ChemComp-8ZD: |
Source |
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![]() | LIGASE / E3 Ligase / HYDROLASE / Ligase / protein binding / Ligase - protein binding complex |