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-Structure paper
Title | Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 8, Page 316-320, Year 2017 |
Publish date | Feb 1, 2017 (structure data deposition date) |
![]() | Lanier, M. / Pickens, J. / Bigi, S.V. / Bradshaw-Pierce, E.L. / Chambers, A. / Cheruvallath, Z.S. / Cole, D. / Dougan, D.R. / Ermolieff, J. / Gibson, T. ...Lanier, M. / Pickens, J. / Bigi, S.V. / Bradshaw-Pierce, E.L. / Chambers, A. / Cheruvallath, Z.S. / Cole, D. / Dougan, D.R. / Ermolieff, J. / Gibson, T. / Halkowycz, P. / Hirokawa, A. / Ivetac, A. / Miura, J. / Nunez, E. / Sabat, M. / Tyhonas, J. / Wang, H. / Wang, X. / Swann, S. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 2.95 Å |
Structure data | ![]() PDB-5uor: ![]() PDB-5uox: ![]() PDB-5up3: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-8GV: ![]() ChemComp-HOH: ![]() ChemComp-8GY: ![]() ChemComp-8GS: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE / METAL-BINDING / APOPTOSIS / TRANSFERASE-TRANSFERASE INHIBITOR complex |