[日本語] English
万見文献
- EMDB/PDB/SASBDBから引用されている文献のデータベース -

+
検索条件

キーワード
構造解析手法
著者・登録者
ジャーナル
IF

-
Structure paper

タイトルAn expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
ジャーナル・号・ページElife, Vol. 7, Year 2018
掲載日2018年8月30日 (構造データの登録日)
著者Keedy, D.A. / Hill, Z.B. / Biel, J.T. / Kang, E. / Rettenmaier, T.J. / Brandao-Neto, J. / Pearce, N.M. / von Delft, F. / Wells, J.A. / Fraser, J.S.
リンクElife / PubMed:29877794
手法X線回折
解像度1.513 - 2.647 Å
構造データ

PDB-5qde:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000740a
手法: X-RAY DIFFRACTION / 解像度: 1.764 Å

PDB-5qdf:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000295a
手法: X-RAY DIFFRACTION / 解像度: 1.712 Å

PDB-5qdg:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000294a
手法: X-RAY DIFFRACTION / 解像度: 1.79 Å

PDB-5qdh:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000004a
手法: X-RAY DIFFRACTION / 解像度: 1.682 Å

PDB-5qdi:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000157a
手法: X-RAY DIFFRACTION / 解像度: 1.623 Å

PDB-5qdj:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000211a
手法: X-RAY DIFFRACTION / 解像度: 1.761 Å

PDB-5qdk:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000069a
手法: X-RAY DIFFRACTION / 解像度: 1.555 Å

PDB-5qdl:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000072a
手法: X-RAY DIFFRACTION / 解像度: 1.833 Å

PDB-5qdm:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000074a
手法: X-RAY DIFFRACTION / 解像度: 2.647 Å

PDB-5qdn:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000163a
手法: X-RAY DIFFRACTION / 解像度: 1.821 Å

PDB-5qdo:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOCR000171b
手法: X-RAY DIFFRACTION / 解像度: 1.792 Å

PDB-5qdp:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000207a
手法: X-RAY DIFFRACTION / 解像度: 1.744 Å

PDB-5qdq:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000847b
手法: X-RAY DIFFRACTION / 解像度: 1.575 Å

PDB-5qdr:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000089a
手法: X-RAY DIFFRACTION / 解像度: 1.784 Å

PDB-5qds:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000108a
手法: X-RAY DIFFRACTION / 解像度: 1.751 Å

PDB-5qdt:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000475a
手法: X-RAY DIFFRACTION / 解像度: 1.821 Å

PDB-5qdu:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000466a
手法: X-RAY DIFFRACTION / 解像度: 1.672 Å

PDB-5qdv:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000574a
手法: X-RAY DIFFRACTION / 解像度: 1.773 Å

PDB-5qdw:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000465a
手法: X-RAY DIFFRACTION / 解像度: 2.212 Å

PDB-5qdx:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000484a
手法: X-RAY DIFFRACTION / 解像度: 2.062 Å

PDB-5qdy:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000599c
手法: X-RAY DIFFRACTION / 解像度: 1.835 Å

PDB-5qdz:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000435a
手法: X-RAY DIFFRACTION / 解像度: 2.141 Å

PDB-5qe0:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000648a
手法: X-RAY DIFFRACTION / 解像度: 1.98 Å

PDB-5qe1:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000645a
手法: X-RAY DIFFRACTION / 解像度: 1.685 Å

PDB-5qe2:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000398a
手法: X-RAY DIFFRACTION / 解像度: 1.787 Å

PDB-5qe3:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000449a
手法: X-RAY DIFFRACTION / 解像度: 1.742 Å

PDB-5qe4:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000514a
手法: X-RAY DIFFRACTION / 解像度: 1.852 Å

PDB-5qe5:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000632a
手法: X-RAY DIFFRACTION / 解像度: 1.773 Å

PDB-5qe6:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000608a
手法: X-RAY DIFFRACTION / 解像度: 1.774 Å

PDB-5qe7:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000601a
手法: X-RAY DIFFRACTION / 解像度: 1.713 Å

PDB-5qe8:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000127a
手法: X-RAY DIFFRACTION / 解像度: 1.813 Å

PDB-5qe9:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000232a
手法: X-RAY DIFFRACTION / 解像度: 1.692 Å

PDB-5qea:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000733a
手法: X-RAY DIFFRACTION / 解像度: 1.743 Å

PDB-5qeb:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000639a
手法: X-RAY DIFFRACTION / 解像度: 1.733 Å

PDB-5qec:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000270a
手法: X-RAY DIFFRACTION / 解像度: 1.673 Å

PDB-5qed:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000538a
手法: X-RAY DIFFRACTION / 解像度: 1.755 Å

PDB-5qee:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000240a
手法: X-RAY DIFFRACTION / 解像度: 1.932 Å

PDB-5qef:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000134a
手法: X-RAY DIFFRACTION / 解像度: 1.605 Å

PDB-5qeg:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000278a
手法: X-RAY DIFFRACTION / 解像度: 1.97 Å

PDB-5qeh:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000323a
手法: X-RAY DIFFRACTION / 解像度: 1.941 Å

PDB-5qei:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_PKTTA024495b
手法: X-RAY DIFFRACTION / 解像度: 1.743 Å

PDB-5qej:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA001247b
手法: X-RAY DIFFRACTION / 解像度: 1.924 Å

PDB-5qek:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOZE000092b
手法: X-RAY DIFFRACTION / 解像度: 1.904 Å

PDB-5qel:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000675b
手法: X-RAY DIFFRACTION / 解像度: 1.654 Å

PDB-5qem:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000217b
手法: X-RAY DIFFRACTION / 解像度: 1.754 Å

PDB-5qen:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000955b
手法: X-RAY DIFFRACTION / 解像度: 1.775 Å

PDB-5qeo:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000657b
手法: X-RAY DIFFRACTION / 解像度: 1.721 Å

PDB-5qep:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000692b
手法: X-RAY DIFFRACTION / 解像度: 1.774 Å

PDB-5qeq:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000245b
手法: X-RAY DIFFRACTION / 解像度: 1.972 Å

PDB-5qer:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000847b
手法: X-RAY DIFFRACTION / 解像度: 1.733 Å

PDB-5qes:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000141a
手法: X-RAY DIFFRACTION / 解像度: 1.745 Å

PDB-5qet:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000017a
手法: X-RAY DIFFRACTION / 解像度: 1.724 Å

PDB-5qeu:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000149a
手法: X-RAY DIFFRACTION / 解像度: 1.735 Å

PDB-5qev:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000603b
手法: X-RAY DIFFRACTION / 解像度: 1.723 Å

PDB-5qew:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000470b
手法: X-RAY DIFFRACTION / 解像度: 1.826 Å

PDB-5qex:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000123a
手法: X-RAY DIFFRACTION / 解像度: 1.673 Å

PDB-5qey:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000708a
手法: X-RAY DIFFRACTION / 解像度: 1.775 Å

PDB-5qez:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000713b
手法: X-RAY DIFFRACTION / 解像度: 1.654 Å

PDB-5qf0:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000216b
手法: X-RAY DIFFRACTION / 解像度: 1.707 Å

PDB-5qf1:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000272b
手法: X-RAY DIFFRACTION / 解像度: 1.844 Å

PDB-5qf2:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000187a
手法: X-RAY DIFFRACTION / 解像度: 1.772 Å

PDB-5qf3:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000194a
手法: X-RAY DIFFRACTION / 解像度: 1.563 Å

PDB-5qf4:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000144a
手法: X-RAY DIFFRACTION / 解像度: 1.832 Å

PDB-5qf5:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA001440b
手法: X-RAY DIFFRACTION / 解像度: 1.725 Å

PDB-5qf6:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000281b
手法: X-RAY DIFFRACTION / 解像度: 1.765 Å

PDB-5qf7:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000951b
手法: X-RAY DIFFRACTION / 解像度: 1.75 Å

PDB-5qf8:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000114a
手法: X-RAY DIFFRACTION / 解像度: 1.987 Å

PDB-5qf9:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000242a
手法: X-RAY DIFFRACTION / 解像度: 1.94 Å

PDB-5qfa:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000752b
手法: X-RAY DIFFRACTION / 解像度: 1.742 Å

PDB-5qfb:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_PKOOA000283c
手法: X-RAY DIFFRACTION / 解像度: 1.851 Å

PDB-5qfc:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000140a
手法: X-RAY DIFFRACTION / 解像度: 1.841 Å

PDB-5qfd:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000505a
手法: X-RAY DIFFRACTION / 解像度: 1.693 Å

PDB-5qfe:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000509a
手法: X-RAY DIFFRACTION / 解像度: 1.563 Å

PDB-5qff:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000515a
手法: X-RAY DIFFRACTION / 解像度: 1.703 Å

PDB-5qfg:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000523a
手法: X-RAY DIFFRACTION / 解像度: 1.654 Å

PDB-5qfh:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000525a
手法: X-RAY DIFFRACTION / 解像度: 1.591 Å

PDB-5qfi:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000531a
手法: X-RAY DIFFRACTION / 解像度: 1.68 Å

PDB-5qfj:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000814b
手法: X-RAY DIFFRACTION / 解像度: 1.954 Å

PDB-5qfk:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000509a
手法: X-RAY DIFFRACTION / 解像度: 1.594 Å

PDB-5qfl:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000206a
手法: X-RAY DIFFRACTION / 解像度: 1.824 Å

PDB-5qfm:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000269a
手法: X-RAY DIFFRACTION / 解像度: 1.83 Å

PDB-5qfn:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000324a
手法: X-RAY DIFFRACTION / 解像度: 1.675 Å

PDB-5qfo:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000644b
手法: X-RAY DIFFRACTION / 解像度: 1.851 Å

PDB-5qfp:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000293a
手法: X-RAY DIFFRACTION / 解像度: 1.771 Å

PDB-5qfq:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000491a
手法: X-RAY DIFFRACTION / 解像度: 1.621 Å

PDB-5qfr:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000497a
手法: X-RAY DIFFRACTION / 解像度: 1.622 Å

PDB-5qfs:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000293a
手法: X-RAY DIFFRACTION / 解像度: 1.853 Å

PDB-5qft:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000683b
手法: X-RAY DIFFRACTION / 解像度: 1.96 Å

PDB-5qfu:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000487a
手法: X-RAY DIFFRACTION / 解像度: 1.613 Å

PDB-5qfv:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000491a
手法: X-RAY DIFFRACTION / 解像度: 1.641 Å

PDB-5qfw:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000497a
手法: X-RAY DIFFRACTION / 解像度: 1.662 Å

PDB-5qfx:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000953b
手法: X-RAY DIFFRACTION / 解像度: 1.824 Å

PDB-5qfy:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000396a
手法: X-RAY DIFFRACTION / 解像度: 1.769 Å

PDB-5qfz:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000711a
手法: X-RAY DIFFRACTION / 解像度: 1.723 Å

PDB-5qg0:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000280c
手法: X-RAY DIFFRACTION / 解像度: 1.753 Å

PDB-5qg1:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000619a
手法: X-RAY DIFFRACTION / 解像度: 2.209 Å

PDB-5qg2:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000275a
手法: X-RAY DIFFRACTION / 解像度: 2.122 Å

PDB-5qg3:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000662a
手法: X-RAY DIFFRACTION / 解像度: 1.654 Å

PDB-5qg4:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000666a
手法: X-RAY DIFFRACTION / 解像度: 1.788 Å

PDB-5qg5:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000811b
手法: X-RAY DIFFRACTION / 解像度: 2.07 Å

PDB-5qg6:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA001176b
手法: X-RAY DIFFRACTION / 解像度: 1.734 Å

PDB-5qg7:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000611a
手法: X-RAY DIFFRACTION / 解像度: 1.811 Å

PDB-5qg8:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000555a
手法: X-RAY DIFFRACTION / 解像度: 1.634 Å

PDB-5qg9:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000595a
手法: X-RAY DIFFRACTION / 解像度: 1.671 Å

PDB-5qga:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000540a
手法: X-RAY DIFFRACTION / 解像度: 1.653 Å

PDB-5qgb:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000628a
手法: X-RAY DIFFRACTION / 解像度: 1.552 Å

PDB-5qgc:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000650a
手法: X-RAY DIFFRACTION / 解像度: 1.586 Å

PDB-5qgd:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000611a
手法: X-RAY DIFFRACTION / 解像度: 1.661 Å

PDB-5qge:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000619a
手法: X-RAY DIFFRACTION / 解像度: 1.703 Å

PDB-5qgf:
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000539a
手法: X-RAY DIFFRACTION / 解像度: 1.513 Å

PDB-6b8e:
Multiconformer model of apo WT PTP1B with glycerol at 180 K
手法: X-RAY DIFFRACTION / 解像度: 1.82 Å

PDB-6b8t:
Multiconformer model of apo WT PTP1B with glycerol at 240 K
手法: X-RAY DIFFRACTION / 解像度: 1.85 Å

PDB-6b8x:
Multiconformer model of apo WT PTP1B with glycerol at 278 K
手法: X-RAY DIFFRACTION / 解像度: 1.74 Å

PDB-6b8z:
Multiconformer model of WT PTP1B with BB3 at 273 K
手法: X-RAY DIFFRACTION / 解像度: 1.8 Å

PDB-6b90:
Multiconformer model of apo WT PTP1B with glycerol at 100 K (ALTERNATIVE REFINEMENT OF PDB 1SUG showing conformational heterogeneity)
手法: X-RAY DIFFRACTION / 解像度: 1.95 Å

PDB-6b95:
Multiconformer model of K197C PTP1B tethered to compound 2 at 100 K
手法: X-RAY DIFFRACTION / 解像度: 1.95 Å

PDB-6bai:
Multiconformer model of apo K197C PTP1B at 100 K
手法: X-RAY DIFFRACTION / 解像度: 1.95 Å

化合物

ChemComp-AWD:
~{N}-(4-fluorophenyl)-4-methyl-piperazine-1-carboxamide / N-(4-フルオロフェニル)-4-メチル-1-ピペラジンカルボアミド

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / トリス(ヒドロキシメチル)メチルアンモニウム / pH緩衝剤*YM / トリスヒドロキシメチルアミノメタン

ChemComp-HOH:
WATER / 水

ChemComp-AWG:
~{N}2-(1~{H}-benzimidazol-2-yl)benzene-1,2-diamine

ChemComp-AWS:
8-[(dimethylamino)methyl]-4-methyl-7-oxidanyl-chromen-2-one

ChemComp-JFJ:
1-(3-chlorophenyl)-N-methylmethanamine / メチル(3-クロロベンジル)アミン

ChemComp-JFM:
N-(2-phenylethyl)methanesulfonamide / N-フェネチルメタンスルホンアミド

ChemComp-JFP:
N-(4-methyl-1,3-thiazol-2-yl)propanamide

ChemComp-JFS:
[4-(1H-benzimidazol-1-yl)phenyl]methanol

ChemComp-JFV:
methyl 2-(4-aminophenoxy)benzoate

ChemComp-AW7:
2-[4-(1~{H}-pyrazol-3-yl)phenoxy]pyrimidine

ChemComp-JFY:
N-{4-[(2S)-butan-2-yl]phenyl}methanesulfonamide

ChemComp-JG4:
2-(thiophen-2-yl)-1H-imidazole / 2-(2-チエニル)-1H-イミダゾ-ル

ChemComp-JGA:
N-ethyl-N'-(5-methyl-1,2-oxazol-3-yl)urea

ChemComp-JGD:
N,N-dimethylpyridin-4-amine / 4-(ジメチルイミニオ)-1,4-ジヒドロピリジン-1-アニオン / 4-ジメチルアミノピリジン

ChemComp-6SU:
methyl 3-(methylsulfonylamino)benzoate / 3-(メチルスルホニルアミノ)安息香酸メチル

ChemComp-JGG:
N-[(4-cyanophenyl)methyl]morpholine-4-carboxamide

ChemComp-GUY:
~{N}-(1-propyl-1,2,3,4-tetrazol-5-yl)furan-2-carboxamide

ChemComp-GV1:
~{N},~{N},5,6-tetramethylthieno[2,3-d]pyrimidin-4-amine

ChemComp-GQP:
1-[(4-fluorophenyl)methyl]benzimidazole / 1-(4-フルオロベンジル)-1H-ベンゾイミダゾ-ル

ChemComp-JGJ:
2-methoxy-N-[(1R)-1-phenylethyl]acetamide / N-[(R)-1-フェニルエチル]-2-メトキシアセトアミド

ChemComp-JGM:
{N}-[(2~{S})-1-diazanyl-3-(4-hydroxyphenyl)-1-oxidanylidene-propan-2-yl]ethanamide

ChemComp-MPV:
1-methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine / 1-メチル-3-(2-チエニル)-1H-ピラゾ-ル-5-アミン

ChemComp-JGP:
(azepan-1-yl)(2H-1,3-benzodioxol-5-yl)methanone

ChemComp-JGS:
3-[(1,2-oxazole-5-carbonyl)amino]benzoic acid

ChemComp-JGV:
(2,3-dihydro-1,2,3-benzothiadiazol-5-yl)(morpholin-4-yl)methanone

ChemComp-JGY:
1-methyl-N-{[(2S)-oxolan-2-yl]methyl}-1H-pyrazole-3-carboxamide

ChemComp-JH1:
1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide

ChemComp-JH4:
N-methylpyrimidin-2-amine / 2-(メチルアミノ)ピリミジン

ChemComp-JH7:
1-methyl-5-(phenylamino)-1,2-dihydro-3H-pyrazol-3-one

ChemComp-JHA:
3-chloro-4-(4-methylpiperidin-1-yl)aniline

ChemComp-JHD:
1-(3,4-dimethoxyphenyl)methanamine / 3,4-ジメトキシベンジルアミン

ChemComp-JHJ:
N-(4-methoxyphenyl)-N'-pyridin-4-ylurea / 1-[(4-メトキシフェニル)]-3-(ピリジン-4-イル)尿素

ChemComp-JHP:
4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide

ChemComp-JHS:
N-[(4-phenyloxan-4-yl)methyl]acetamide

ChemComp-JHV:
4-chloro-N~1~-(pyridin-4-yl)benzene-1,2-diamine

ChemComp-02S:
4-(benzyloxy)benzoic acid / 4-(ベンジルオキシ)安息香酸

ChemComp-7MU:
4-chloranyl-~{N}-methyl-pyridine-2-carboxamide / N-メチル-4-クロロピリジン-2-カルボアミド

ChemComp-JJ4:
3-cyclopentyl-N-(5-methyl-1,3-thiazol-2-yl)propanamide

ChemComp-JJ7:
1-{4-[(2-methoxyethyl)amino]piperidin-1-yl}ethan-1-one

ChemComp-GRY:
~{N}1-(4,6-dimethylpyrimidin-2-yl)benzene-1,4-diamine

ChemComp-JJG:
4-[2-(phenylsulfanyl)ethyl]morpholine / フェニル(2-モルホリノエチル)スルフィド

ChemComp-JJM:
1-methyl-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

ChemComp-JKP:
2,6-dichloropyridine-4-carboxylic acid / 2,6-ジクロロイソニコチン酸

ChemComp-ES7:
1-methyl-1H-benzimidazol-2-amine / 1-メチル-1H-ベンゾイミダゾ-ル-2-アミン

ChemComp-JKS:
5-(pyrrolidin-1-yl)pyridine-2-carbonitrile

ChemComp-JLG:
2-(thiophen-2-yl)-1,3-thiazole-4-carboxylic acid

ChemComp-JLD:
[(3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl]methanol / (3S)-1-メチル-4α-(4-フルオロフェニル)ピペリジン-3β-メタノ-ル

ChemComp-JLA:
4-(piperidin-1-yl)benzoic acid / 4-ピペリジノ安息香酸

ChemComp-JL7:
2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylic acid

ChemComp-JL4:
5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid

ChemComp-JL1:
2-[(4-methylphenyl)sulfanyl]pyridine-3-carboxylic acid / 2-(4-メチルフェニルチオ)ピリジン-3-カルボン酸

ChemComp-6RO:
~{N}-(4-chlorophenyl)methanesulfonamide / N-(4-クロロフェニル)メタンスルホンアミド

ChemComp-DSJ:
1-(4-amino-2-hydroxyphenyl)ethan-1-one / 4′-アミノ-2′-ヒドロキシアセトフェノン

ChemComp-JKY:
N-[(4-chlorophenyl)methyl]methanesulfonamide / N-(4-クロロベンジル)メタンスルホンアミド

ChemComp-JKV:
3-(4-chlorophenyl)-1H-pyrazol-5-amine / 3-(4-クロロフェニル)-1H-ピラゾ-ル-5-アミン

ChemComp-JMV:
(3-chlorophenoxy)acetic acid / 3-クロロフェノキシ酢酸

ChemComp-JMM:
[4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone

ChemComp-JMJ:
N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]furan-2-carboxamide

ChemComp-2O8:
4-[(trifluoromethyl)sulfanyl]benzamide

ChemComp-JMG:
5-phenylthiophene-2-carboxylic acid / 5-フェニルチオフェン-2-カルボン酸

ChemComp-JMD:
4-(2-hydroxyethyl)benzonitrile / 4-(2-ヒドロキシエチル)ベンゾニトリル

ChemComp-JMA:
4-(5,6-dichloro-1H-benzimidazol-1-yl)butan-1-ol

ChemComp-JLY:
4-(4-methoxyphenyl)-6,7-dihydrothieno[3,2-c]pyridine

ChemComp-JLV:
N-cyclohexyl-N'-methylthiourea / 1-メチル-3-シクロヘキシルチオ尿素

ChemComp-JLM:
3-methyl-1-benzofuran-2-carboxylic acid / 3-メチルベンゾフラン-2-カルボン酸

ChemComp-JNY:
6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile / 2-オキソ-4-(トリフルオロメチル)-6-メチル-1,2-ジヒドロ-ピリジン-3-カルボニトリル

ChemComp-JNV:
1-(3,4-dichlorophenyl)propan-2-one / 3,4-ジクロロフェニルアセトン

ChemComp-JNP:
7-hydroxy-2,2-dimethyl-2,3-dihydro-4H-1-benzopyran-4-one / 2,2-ジメチル-7-ヒドロキシ-2,3-ジヒドロ-4H-1-ベンゾピラン-4-オン

ChemComp-JNM:
1-(2,6-dihydroxy-3-propylphenyl)ethan-1-one

ChemComp-JNG:
[(4-chlorophenyl)sulfanyl]acetic acid / (4-クロロフェニルチオ)酢酸

ChemComp-JND:
6-ethylthieno[2,3-d]pyrimidin-4(3H)-one / 6-エチル-3,4-ジヒドロチエノ[2,3-d]ピリミジン-4-オン

ChemComp-JNA:
N-[(thiophen-2-yl)methyl]benzenesulfonamide

ChemComp-JN1:
(6R)-5,6-dihydro-1H-2,6-methano-1lambda~6~-1lambda~6~,2,5-benzothiadiazocine-1,1,4(3H)-trione

ChemComp-JJP:
(2S,5S,6R)-7-methyl-2,3,4,5,6,7-hexahydro-1H-2,6-methanoazocino[5,4-b]indol-5-ol

ChemComp-JMY:
1-[(3S,3aS,8bS)-5-fluoro-3-(hydroxymethyl)-2,3,3a,8b-tetrahydro-1H-[1]benzofuro[3,2-b]pyrrol-1-yl]ethan-1-one

ChemComp-JOA:
(1R,4R,5R,6R)-4,6-dimethoxy-2-(methylsulfonyl)-2-azabicyclo[3.3.1]nonane

ChemComp-JOD:
(5S,8R,8aS)-8-hydroxyhexahydro-3H-5,8-ethano[1,3]oxazolo[3,4-a]pyridin-3-one

ChemComp-JOG:
(1R,4R,5R,6S)-4,6-dihydroxy-N-phenyl-2-azabicyclo[3.3.1]nonane-2-carboxamide

ChemComp-JOJ:
2-(4,5-dichloro-1H-imidazol-1-yl)ethanethioamide

ChemComp-JOM:
5-{[4-(trifluoromethyl)phenyl]amino}-1,3,4-thiadiazole-2(3H)-thione

ChemComp-JOP:
N-[(1R,2S,4S)-bicyclo[2.2.1]heptan-2-yl]-N'-[(2R)-2-hydroxypropyl]thiourea

ChemComp-JOV:
3-chloro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide

ChemComp-8H8:
2-fluoro-4-hydroxybenzonitrile / 3-フルオロ-4-シアノフェノ-ル

ChemComp-JJY:
3,4,6,7-tetrahydroacridine-1,8(2H,5H)-dione / 3,4,5,6-テトラヒドロアクリジン-1,8(2H,7H)-ジオン

ChemComp-JK7:
N-[(1S,2S,3S,4R)-3-hydroxy-1,2,3,4-tetrahydro-1,4-epoxynaphthalen-2-yl]cyclobutanecarboxamide

ChemComp-JKA:
(1S,4R,5S,6R)-2-(methylsulfonyl)-2-azabicyclo[3.3.1]nonane-4,6-diol

ChemComp-JOY:
4-[(1H-pyrazol-1-yl)methyl]benzonitrile / 4-(1H-ピラゾ-ル-1-イルメチル)ベンゾニトリル

ChemComp-JO7:
(1R,4R,5R,6R)-4-methoxy-2-(methylsulfonyl)-2-azabicyclo[3.3.1]nonan-6-ol

ChemComp-JO4:
4-phenoxybenzoic acid / 4-フェノキシ安息香酸

ChemComp-JO1:
1-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-5-carboxamide

ChemComp-GW1:
(4-chloranyl-2-methyl-pyrazol-3-yl)-piperidin-1-yl-methanone

ChemComp-JP4:
[2-(morpholin-4-yl)phenyl]methanol

ChemComp-JKG:
4-({[(thiophen-2-yl)methyl]amino}methyl)phenol

ChemComp-H5A:
3,4,5-trimethoxybenzoic acid / 3,4,5-トリメトキシ安息香酸 / オイデスミン酸

ChemComp-JP7:
(6aR,12aR)-3-methoxy-6a,10,11,12a-tetrahydro-6H,7H,9H-[1]benzopyrano[4,3-c]pyrazolo[1,2-a]pyrazol-9-one

ChemComp-JPD:
methyl (1S,3S,4R)-4-hydroxy-3-[(1S)-1-hydroxypropyl]-2-azabicyclo[2.2.2]octane-2-carboxylate

ChemComp-0R0:
2-hydroxybenzonitrile / 2-ヒドロキシベンゾニトリル

ChemComp-JPG:
1-(2-phenoxyphenyl)ethan-1-one / 2-アセチルジフェニルエ-テル

ChemComp-JKJ:
(1R,3R,4S)-3-(methoxymethyl)-2-(methylsulfonyl)-2-azabicyclo[2.2.2]octan-4-ol

ChemComp-JPV:
(2R,5R,6S)-2,3,4,5,6,7-hexahydro-1H-2,6-methanoazocino[5,4-b]indol-5-ol

ChemComp-JQ4:
(1S,3S,4R)-3-[(1S)-1-hydroxypropyl]-2-(methylsulfonyl)-2-azabicyclo[2.2.2]octan-4-ol

ChemComp-JQ7:
2-[(4R)-4-hydroxy-1,1-dioxo-3,4-dihydro-1lambda~6~,2-benzothiazin-2(1H)-yl]acetamide

ChemComp-JQA:
(4R,4aR,6R,8aR)-1-benzyloctahydro-2H-6,4-(epiminomethano)-3,1-benzoxazin-2-one

ChemComp-JQD:
(6aS,12aR)-3-methoxy-6a,10,11,12a-tetrahydro-6H,7H,9H-[1]benzopyrano[4,3-c]pyrazolo[1,2-a]pyrazol-9-one

ChemComp-F8D:
1-[(3S,3aS,8bS)-7-chloro-3-(hydroxymethyl)-2,3,3a,8b-tetrahydro-1H-[1]benzofuro[3,2-b]pyrrol-1-yl]ethan-1-one

ChemComp-GOL:
GLYCEROL / グリセロ-ル / グリセリン

ChemComp-FRJ:
3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE / N-[4-(2-チアゾリルスルファモイル)フェニル]-2-エチル-3-(4-ヒドロキシ-3,5-ジブロモベンゾイル)ベ(以下略)

ChemComp-D0P:
N-(2',4'-difluoro-4-hydroxy[1,1'-biphenyl]-3-yl)-2-sulfanylacetamide

由来
  • homo sapiens (ヒト)
キーワードHYDROLASE (加水分解酵素) / PanDDA / SGC - Diamond I04-1 fragment screening / protein tyrosine phosphatase (プロテインチロシンホスファターゼ) / PTP / protein tyrosine phosphatase 1B / PTP1B / enzyme (酵素) / allostery (アロステリック効果) / multiconformer / multitemperature / SIGNALING PROTEIN / tethering (テザリング) / covalent ligand

+
万見文献について

-
お知らせ

-
2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

-
2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

+
2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

+
2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

+
2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

-
万見文献

EMDB/PDB/SASBDBから引用されている文献のデータベース

  • EMDB/PDB/SASBDBのエントリから引用されている文献のデータベースです
  • Pubmedのデータを利用しています

関連情報:EMDB / PDB / SASBDB / 万見 (Yorodumi) / EMN文献 / 新しいEM Navigatorと万見の変更点

他の情報も見る