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TitleFluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways.
Journal, issue, pagesAcs Chem. Biol., Vol. 14, Page 369-377, Year 2019
Publish dateJul 12, 2017 (structure data deposition date)
AuthorsChisholm, D.R. / Tomlinson, C.W.E. / Zhou, G.L. / Holden, C. / Affleck, V. / Lamb, R. / Newling, K. / Ashton, P. / Valentine, R. / Redfern, C. ...Chisholm, D.R. / Tomlinson, C.W.E. / Zhou, G.L. / Holden, C. / Affleck, V. / Lamb, R. / Newling, K. / Ashton, P. / Valentine, R. / Redfern, C. / Erostyak, J. / Makkai, G. / Ambler, C.A. / Whiting, A. / Pohl, E.
External linksAcs Chem. Biol. / PubMed:30707838
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-5ogb:
Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360.
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-9U5:
4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Retinoid / Fluorescent / DC360 / CRABPII

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