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Structure paper

TitleMolecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 3117-3126, Year 2019
Publish dateJun 29, 2017 (structure data deposition date)
AuthorsBou-Nader, C. / Barraud, P. / Pecqueur, L. / Perez, J. / Velours, C. / Shepard, W. / Fontecave, M. / Tisne, C. / Hamdane, D.
External linksNucleic Acids Res. / PubMed:30605527
MethodsX-ray diffraction
Resolution1.71 - 3.2 Å
Structure data

PDB-5oc4:
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

PDB-5oc5:
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD K419A-K420A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.893 Å

PDB-5oc6:
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD in complex with a 22 nucleotide dsRNA
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CAC:
CACODYLATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA BINDING PROTEIN / double-stranded RNA-binding domain / double-stranded RNA-binding domain protein-RNA complex dsRNA

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