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-Structure paper
Title | Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 5857-5867, Year 2017 |
Publish date | Feb 7, 2017 (structure data deposition date) |
Authors | Guzik, K. / Zak, K.M. / Grudnik, P. / Magiera, K. / Musielak, B. / Torner, R. / Skalniak, L. / Domling, A. / Dubin, G. / Holak, T.A. |
External links | J. Med. Chem. / PubMed:28613862 |
Methods | X-ray diffraction |
Resolution | 1.7 - 2.35 Å |
Structure data | PDB-5n2d: PDB-5n2f: |
Chemicals | ChemComp-8J8: ChemComp-HOH: ChemComp-8HW: |
Source |
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Keywords | CELL CYCLE / PD-L1 / PD-1 / small-molecule inhibitor / IMMUNE SYSTEM |