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Structure paper

TitleThe structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor.
Journal, issue, pagesActa Crystallogr F Struct Biol Commun, Vol. 72, Page 813-819, Year 2016
Publish dateAug 25, 2016 (structure data deposition date)
AuthorsChristopeit, T. / Yang, K.W. / Yang, S.K. / Leiros, H.K.
External linksActa Crystallogr F Struct Biol Commun / PubMed:27834790
MethodsX-ray diffraction
Resolution1.497 Å
Structure data

PDB-5lsc:
The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.497 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-752:
2-[5-[2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-ethyl]sulfanyl-4~{H}-1,2,4-triazol-3-yl]benzoic acid

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / Antibiotic resistance / Carbapenemases / Verona integron-encoded metallo-beta-lactamase 2 / VIM-2

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