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-Structure paper
Title | Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. |
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Journal, issue, pages | Sci Adv, Vol. 2, Page e1601017-e1601017, Year 2016 |
Publish date | Apr 10, 2016 (structure data deposition date) |
![]() | Speranzini, V. / Rotili, D. / Ciossani, G. / Pilotto, S. / Marrocco, B. / Forgione, M. / Lucidi, A. / Forneris, F. / Mehdipour, P. / Velankar, S. ...Speranzini, V. / Rotili, D. / Ciossani, G. / Pilotto, S. / Marrocco, B. / Forgione, M. / Lucidi, A. / Forneris, F. / Mehdipour, P. / Velankar, S. / Mai, A. / Mattevi, A. |
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Methods | X-ray diffraction |
Resolution | 2.8 - 3.5 Å |
Structure data | ![]() PDB-5l3e: ![]() PDB-5l3f: ![]() PDB-5l3g: ![]() PDB-5lbq: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-E11: ![]() ChemComp-NA: ![]() ChemComp-767: |
Source |
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![]() | OXIDOREDUCTASE/REPRESSOR / OXIDOREDUCTASE-REPRESSOR complex / LSD1 / KDM1A / CoREST1 / chromatin / epigenetic / OXIDOREDUCTASE |