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Structure paper

TitleMolecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase.
Journal, issue, pagesHum. Mol. Genet., Vol. 25, Page 2234-2244, Year 2016
Publish dateMar 7, 2016 (structure data deposition date)
AuthorsMcCorvie, T.J. / Kopec, J. / Pey, A.L. / Fitzpatrick, F. / Patel, D. / Chalk, R. / Shrestha, L. / Yue, W.W.
External linksHum. Mol. Genet. / PubMed:27005423
MethodsX-ray diffraction
Resolution1.73 Å
Structure data

PDB-5in3:
Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-H2U:
5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-G1P:
1-O-phosphono-alpha-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / GALT / UMP-GALT / glucose-1-phosphate / galactose-1-phosphate uridylyltransferase

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