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TitleTargeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells
Journal, issue, pagesSci Rep, Vol. 7, Page 5609-5609, Year 2017
Publish dateOct 4, 2016 (structure data deposition date)
AuthorsFujikawa, A. / Sugawara, H. / Tanaka, T. / Matsumoto, M. / Kuboyama, K. / Suzuki, R. / Tanga, N. / Ogata, A. / Masumura, M. / Noda, M.
External linksSci Rep / PubMed:28717188
MethodsX-ray diffraction
Resolution2.53 Å
Structure data

PDB-5h08:
Human PTPRZ D1 domain complexed with NAZ2329
Method: X-RAY DIFFRACTION / Resolution: 2.53 Å

Chemicals

ChemComp-7WL:
3-{[2-Ethoxy-5-(trifluoromethyl)benzyl]sulfanyl}-N-(phenylsulfonyl)thiophene-2-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Protein Tyrosine Phosphatase / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex

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