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Structure paper

TitleRational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
Journal, issue, pagesACS Chem. Biol., Vol. 13, Page 600-608, Year 2018
Publish dateJul 21, 2016 (structure data deposition date)
AuthorsPorkolab, V. / Chabrol, E. / Varga, N. / Ordanini, S. / Sutkeviciu Te, I. / Thepaut, M. / Garcia-Jimenez, M.J. / Girard, E. / Nieto, P.M. / Bernardi, A. / Fieschi, F.
External linksACS Chem. Biol. / PubMed:29272097
MethodsX-ray diffraction
Resolution1.844 Å
Structure data

PDB-5g6u:
Crystal structure of langerin carbohydrate recognition domain with GlcNS6S
Method: X-RAY DIFFRACTION / Resolution: 1.844 Å

Chemicals

ChemComp-TRP:
TRYPTOPHAN

ChemComp-SGN:
2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose

ChemComp-EU:
EUROPIUM ION

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCARBOHYDRATE BINDING PROTEIN / LANGERIN / CD207 / CLEC4K / C-TYPE LECTINS / CLRS / SULFATED CARBOHYDRATES

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