Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Journal, issue, pages	Nat. Chem. Biol., Vol. 12, Page 539-, Year 2016
Publish date	Dec 22, 2014 (structure data deposition date)
Authors	Johansson, C. / Velupillai, S. / Tumber, A. / Szykowska, A. / Hookway, E.S. / Nowak, R.P. / Strain-Damerell, C. / Gileadi, C. / Philpott, M. / Burgess-Brown, N. ...Johansson, C. / Velupillai, S. / Tumber, A. / Szykowska, A. / Hookway, E.S. / Nowak, R.P. / Strain-Damerell, C. / Gileadi, C. / Philpott, M. / Burgess-Brown, N. / Wu, N. / Kopec, J. / Nuzzi, A. / Steuber, H. / Egner, U. / Badock, V. / Munro, S. / Lathangue, N.B. / Westaway, S. / Brown, J. / Athanasou, N. / Prinjha, R. / Brennan, P.E. / Oppermann, U.
External links	Nat. Chem. Biol. / PubMed:27214403
Methods	X-ray diffraction
Resolution	1.78 - 2.44 Å
Structure data	PDB-4uf0: Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid. Method: X-RAY DIFFRACTION / Resolution: 1.78 Å PDB-5a1f: Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine. Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-5a3p: Crystal structure of the catalytic domain of human PLU1 (JARID1B). Method: X-RAY DIFFRACTION / Resolution: 2.008 Å PDB-5a3t: Crystal structure of human PLU-1 (JARID1B) in complex with KDM5-C49 (2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl) isonicotinic acid). Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-5a3w: Crystal structure of human PLU-1 (JARID1B) in complex with Pyridine-2, 6-dicarboxylic Acid (PDCA) Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-5fpu: Crystal structure of human JARID1B in complex with GSKJ1 Method: X-RAY DIFFRACTION / Resolution: 2.24 Å PDB-5fpv: Crystal structure of human JMJD2A in complex with compound KDOAM20A Method: X-RAY DIFFRACTION / Resolution: 2.44 Å PDB-5fun: Crystal structure of human JARID1B in complex with GSK467 Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-5fup: Crystal structure of human JARID1B in complex with 2-oxoglutarate. Method: X-RAY DIFFRACTION / Resolution: 2.15 Å PDB-5fv3: Crystal structure of human JARID1B construct c2 in complex with N- Oxalylglycine. Method: X-RAY DIFFRACTION / Resolution: 2.37 Å PDB-5fwj: Crystal structure of human JARID1C in complex with KDM5-C49 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å
Chemicals	ChemComp-FE2: Unknown entry ChemComp-MMK: 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid ChemComp-ZN: Unknown entry ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-HOH: WATER ChemComp-OGA: N-OXALYLGLYCINE / inhibitorYM ChemComp-MN: Unknown entry ChemComp-PO4: PHOSPHATE ION ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH bufferYM ChemComp-NI: NICKEL (II) ION ChemComp-NA: Unknown entry ChemComp-PD2: PYRIDINE-2,4-DICARBOXYLIC ACID ChemComp-K0I: 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid ChemComp-GZA: 2-[(1-benzyl-1H-pyrazol-4-yl)oxy]pyrido[3,4-d]pyrimidin-4(3H)-one ChemComp-CL: Unknown entry ChemComp-AKG: 2-OXOGLUTARIC ACID ChemComp-DMS: DIMETHYL SULFOXIDE / DMSO, precipitantYM ChemComp-MG*: Unknown entry
Source	homo sapiens (human)
Keywords	OXIDOREDUCTASE / LYSINE-SPECIFIC DEMETHYLASE 5B / TRANSCRIPTION / JMJD2A / KDM4A / JARID1B / PLU1 / LYSINE-SPECIFIC / LYSINE-SPECIFIC DEMETHYLASE 5C