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-Structure paper
Title | Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. |
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Journal, issue, pages | Mol. Cell, Vol. 61, Page 329-340, Year 2016 |
Publish date | Dec 4, 2015 (structure data deposition date) |
![]() | Cho, S. / Dickey, S.W. / Urban, S. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.5 Å |
Structure data | ![]() PDB-5f5b: ![]() PDB-5f5d: ![]() PDB-5f5g: ![]() PDB-5f5j: ![]() PDB-5f5k: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / Rhomboid / membrane protease / aldehyde inhibitor / HYDROLASE-INHIBITOR complex / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE / Intramembrane protease / Bicelle / GlpG |