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TitleCrystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand
Journal, issue, pagesTo Be Published
Publish dateOct 12, 2015 (structure data deposition date)
AuthorsFilippakopoulos, P. / Picaud, S. / von Delft, F. / Arrowsmith, C.H. / Edwards, A. / Bountra, C. / Owen, D. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.87 Å
Structure data

PDB-5e7d:
Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

Chemicals

ChemComp-5KL:
(2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Bromodomain / chemical probe / ligand / inhibitor / structural genomics consortium / SGC

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