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TitleTriazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.
Journal, issue, pagesBioorg. Chem., Vol. 63, Page 152-165, Year 2015
Publish dateSep 29, 2015 (structure data deposition date)
AuthorsChatzileontiadou, D.S. / Parmenopoulou, V. / Manta, S. / Kantsadi, A.L. / Kylindri, P. / Griniezaki, M. / Kontopoulou, F. / Telopoulou, A. / Prokova, H. / Panagopoulos, D. ...Chatzileontiadou, D.S. / Parmenopoulou, V. / Manta, S. / Kantsadi, A.L. / Kylindri, P. / Griniezaki, M. / Kontopoulou, F. / Telopoulou, A. / Prokova, H. / Panagopoulos, D. / Boix, E. / Balatsos, N.A. / Komiotis, D. / Leonidas, D.D.
External linksBioorg. Chem. / PubMed:26551065
MethodsX-ray diffraction
Resolution1.34 Å
Structure data

PDB-5e13:
Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c
Method: X-RAY DIFFRACTION / Resolution: 1.34 Å

Chemicals

ChemComp-5J9:
3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / nuclease

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