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Structure paper

TitleStructures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 7148-7153, Year 2016
Publish dateSep 23, 2015 (structure data deposition date)
AuthorsMiao, Y. / Tenor, J.L. / Toffaletti, D.L. / Washington, E.J. / Liu, J. / Shadrick, W.R. / Schumacher, M.A. / Lee, R.E. / Perfect, J.R. / Brennan, R.G.
External linksProc. Natl. Acad. Sci. USA / PubMed:27307435
MethodsX-ray diffraction
Resolution1.573 - 2.563 Å
Structure data

PDB-5dx9:
Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-5dxf:
Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 2.563 Å

PDB-5dxi:
Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5dxl:
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 1
Method: X-RAY DIFFRACTION / Resolution: 1.573 Å

PDB-5dxn:
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-5dxo:
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

ChemComp-BEF:
BERYLLIUM TRIFLUORIDE ION

Source
  • cryptococcus neoformans (Cryptococcus neoformans serotype A)
  • candida albicans (strain sc5314 / atcc mya-2876) (yeast)
  • candida albicans (yeast)
  • neosartorya fumigata (mold)
KeywordsHYDROLASE / trehalose-6-phosphate / phosphatase / trehalose-6-phosphate phosphatase

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