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TitleMechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 7617-7622, Year 2017
Publish dateSep 14, 2015 (structure data deposition date)
AuthorsPham, T.V. / Murkin, A.S. / Moynihan, M.M. / Harris, L. / Tyler, P.C. / Shetty, N. / Sacchettini, J.C. / Huang, H.L. / Meek, T.D.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28679637
MethodsX-ray diffraction
Resolution1.782 Å
Structure data

PDB-5dql:
Crystal Structure of 2-vinyl glyoxylate modified isocitrate lyase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.782 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-VGX:
4-hydroxy-2-oxobutanoic acid

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (strain atcc 35801 / tmc 107 / erdman) (bacteria)
KeywordsLYASE/LYASE INHIBITOR / LYASE-LYASE INHIBITOR complex

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