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-Structure paper
Title | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. |
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Journal, issue, pages | Sci Rep, Vol. 6, Page 27060-27060, Year 2016 |
Publish date | Aug 3, 2015 (structure data deposition date) |
![]() | Gunzburg, M.J. / Kulkarni, K. / Watson, G.M. / Ambaye, N.D. / Del Borgo, M.P. / Brandt, R. / Pero, S.C. / Perlmutter, P. / Wilce, M.C. / Wilce, J.A. |
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Methods | X-ray diffraction |
Resolution | 1.6 - 2.6 Å |
Structure data | ![]() PDB-5d0j: ![]() PDB-5eel: ![]() PDB-5eeq: |
Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-HOH: ![]() ChemComp-MLA: ![]() ChemComp-FMT: ![]() ChemComp-NA: |
Source |
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![]() | SIGNALING PROTEIN / inhibitor / SH2 / Signaling Protein/Peptide / bicyclic / Signaling Protein-Peptide complex / Signaling Protein/Inhibitor / staple / Signaling Protein-Inhibitor complex |