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-Structure paper
Title | Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 25, Page 4642-4647, Year 2015 |
Publish date | Jul 29, 2015 (structure data deposition date) |
Authors | Thoma, G. / Veenstra, S. / Strang, R. / Blanz, J. / Vangrevelinghe, E. / Berghausen, J. / Lee, C.C. / Zerwes, H.G. |
External links | Bioorg. Med. Chem. Lett. / PubMed:26320624 |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.9 Å |
Structure data | PDB-5cxh: PDB-5cxz: PDB-5cy3: |
Chemicals | ChemComp-55M: ChemComp-HOH: ChemComp-GOL: ChemComp-CL: ChemComp-55U: ChemComp-55Y: |
Source |
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Keywords | Transferase/Transferase inhibitor / Transferase-Transferase inhibitor complex |