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Structure paper

TitleAn Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 55, Page 7441-7444, Year 2016
Publish dateJul 21, 2015 (structure data deposition date)
AuthorsMa, Z. / Palermo, G. / Adhireksan, Z. / Murray, B.S. / von Erlach, T. / Dyson, P.J. / Rothlisberger, U. / Davey, C.A.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:27184539
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-5cp6:
Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-RUH:
(ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • xenopus laevis (African clawed frog)
  • synthetic construct (others)
KeywordsSTRUCTURAL PROTEIN/DNA / nucleosome core particle / antitumour compound / STRUCTURAL PROTEIN-DNA complex

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