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Title | Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2). |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 25, Page 4265-4269, Year 2015 |
Publish date | May 28, 2015 (structure data deposition date) |
![]() | Liu, Q. / Batt, D.G. / Lippy, J.S. / Surti, N. / Tebben, A.J. / Muckelbauer, J.K. / Chen, L. / An, Y. / Chang, C. / Pokross, M. ...Liu, Q. / Batt, D.G. / Lippy, J.S. / Surti, N. / Tebben, A.J. / Muckelbauer, J.K. / Chen, L. / An, Y. / Chang, C. / Pokross, M. / Yang, Z. / Wang, H. / Burke, J.R. / Carter, P.H. / Tino, J.A. |
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Methods | X-ray diffraction |
Resolution | 1.57 - 2.31 Å |
Structure data | ![]() PDB-5bpy: ![]() PDB-5bq0: |
Chemicals | ![]() ChemComp-4UQ: ![]() ChemComp-HOH: ![]() ChemComp-4US: ![]() ChemComp-DMS: ![]() ChemComp-EDO: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / KINASE / INHIBITOR / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR complex |