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TitleCancer Differentiating Agent Hexamethylene Bisacetamide Inhibits Bet Bromodomain Proteins.
Journal, issue, pagesCancer Res., Vol. 76, Page 2376-, Year 2016
Publish dateJul 3, 2015 (structure data deposition date)
AuthorsNilsson, L.M. / Green, L.C. / Muralidharan, S.V. / Demir, D. / Welin, M. / Bhadury, J. / Logan, D.T. / Walse, B. / Nilsson, J.A.
External linksCancer Res. / PubMed:26941288
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-5a7c:
Crystal structure of the second bromodomain of human BRD3 in complex with compound
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-5D4:
N-(6-ACETAMIDOHEXYL)ACETAMIDE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / BRD3 / BROMODOMAIN CONTAINING PROTEIN 3 / RING3-LIKE PROTEIN / BRD3 DOMAIN 2

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