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TitleHigher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.
Journal, issue, pagesStructure, Vol. 24, Page 469-476, Year 2016
Publish dateMay 20, 2015 (structure data deposition date)
AuthorsCroll, T.I. / Smith, B.J. / Margetts, M.B. / Whittaker, J. / Weiss, M.A. / Ward, C.W. / Lawrence, M.C.
External linksStructure / PubMed:26853939
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-4zxb:
Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsHORMONE RECEPTOR/IMMUNE SYSTEM / receptor tyrosine kinase extracellular domain antibody fragments / HORMONE RECEPTOR-IMMUNE SYSTEM complex

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