Movie
Controller
Structure viewers
About Yorodumi Papers
+Search query
-Structure paper
| Title | Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition. |
|---|---|
| Journal, issue, pages | Nat. Chem. Biol., Vol. 12, Page 779-786, Year 2016 |
| Publish date | May 18, 2015 (structure data deposition date) |
 Authors | Boudreau, A. / Purkey, H.E. / Hitz, A. / Robarge, K. / Peterson, D. / Labadie, S. / Kwong, M. / Hong, R. / Gao, M. / Del Nagro, C. ...Boudreau, A. / Purkey, H.E. / Hitz, A. / Robarge, K. / Peterson, D. / Labadie, S. / Kwong, M. / Hong, R. / Gao, M. / Del Nagro, C. / Pusapati, R. / Ma, S. / Salphati, L. / Pang, J. / Zhou, A. / Lai, T. / Li, Y. / Chen, Z. / Wei, B. / Yen, I. / Sideris, S. / McCleland, M. / Firestein, R. / Corson, L. / Vanderbilt, A. / Williams, S. / Daemen, A. / Belvin, M. / Eigenbrot, C. / Jackson, P.K. / Malek, S. / Hatzivassiliou, G. / Sampath, D. / Evangelista, M. / O'Brien, T. |
 External links | Nat. Chem. Biol. / PubMed:27479743 |
| Methods | X-ray diffraction |
| Resolution | 2.2 Å |
| Structure data |  PDB-4zvv: |
| Chemicals |  ChemComp-NAD:  ChemComp-SO4:  ChemComp-GN0:  ChemComp-HOH: |
| Source |
|
 Keywords | Oxidoreductase/Oxidoreductase Inhibitor / oxidoreductase inhibitor complex / LDHA-G02792140 / Oxidoreductase-Oxidoreductase Inhibitor complex |
homo sapiens (human)