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-Structure paper
Title | Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 6131-6150, Year 2015 |
Publish date | Mar 6, 2015 (structure data deposition date) |
Authors | Krogsgaard-Larsen, N. / Storgaard, M. / Moller, C. / Demmer, C.S. / Hansen, J. / Han, L. / Monrad, R.N. / Nielsen, B. / Tapken, D. / Pickering, D.S. ...Krogsgaard-Larsen, N. / Storgaard, M. / Moller, C. / Demmer, C.S. / Hansen, J. / Han, L. / Monrad, R.N. / Nielsen, B. / Tapken, D. / Pickering, D.S. / Kastrup, J.S. / Frydenvang, K. / Bunch, L. |
External links | J. Med. Chem. / PubMed:26200741 |
Methods | X-ray diffraction |
Resolution | 1.895 - 1.93 Å |
Structure data | PDB-4yma: PDB-4ymb: |
Chemicals | ChemComp-SO4: ChemComp-GOL: ChemComp-4E5: ChemComp-EDO: ChemComp-ACT: ChemComp-HOH: ChemComp-4E7: ChemComp-CL: ChemComp-PEG: |
Source |
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Keywords | SIGNALING PROTEIN / Ionotropic glutamate receptor / AMPA receptor GluA2 / ligand-binding domain / antagonist / kainate receptor GluK1 / fusion protein |