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Structure paper

TitleStructural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.
Journal, issue, pagesFebs J., Vol. 282, Page 3348-3367, Year 2015
Publish dateMar 6, 2015 (structure data deposition date)
AuthorsBum-Erdene, K. / Leffler, H. / Nilsson, U.J. / Blanchard, H.
External linksFebs J. / PubMed:26077389
MethodsX-ray diffraction
Resolution1.89 - 2.3 Å
Structure data

PDB-4ylz:
Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lacto-N-neotetraose (LNnT)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4ym0:
Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lacto-N-tetraose (LNT)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4ym1:
Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with 2'-fucosyllactose
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4ym2:
Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lactose-3'-sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4ym3:
Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lactose
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / galectin / lectin / carbohydrate binding protein / lacto-N-neotetraose / carbohydrate recognition / beta sandwich / glycosphingolipid / lacto-N-tetraose / H-antigen / sulfated saccharide / lactose

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