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TitleKinetic gating mechanism of DNA damage recognition by Rad4/XPC.
Journal, issue, pagesNat Commun, Vol. 6, Page 5849-, Year 2015
Publish dateMar 2, 2015 (structure data deposition date)
AuthorsChen, X. / Velmurugu, Y. / Zheng, G. / Park, B. / Shim, Y. / Kim, Y. / Liu, L. / Van Houten, B. / He, C. / Ansari, A. / Min, J.H.
External linksNat Commun / PubMed:25562780
MethodsX-ray diffraction
Resolution3.0501 - 4.597 Å
Structure data

PDB-4yir:
Crystal structure of Rad4-Rad23 crosslinked to an undamaged DNA
Method: X-RAY DIFFRACTION / Resolution: 3.0501 Å

PDB-6ubf:
Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
Method: X-RAY DIFFRACTION / Resolution: 4.597 Å

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • synthetic construct (others)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsDNA BINDING PROTEIN/DNA / DNA damage repair / nucleotide excision repair / protein-DNA interactions / protein-DNA crosslinking / protein-DNA complex / xeroderma pigmentosum / beta-hairpin / transglutaminase domain / disulfide crosslinking / DNA BINDING PROTEIN-DNA complex / Beta hairpin motif / chemical crosslinking

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