+Search query
-Structure paper
Title | Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYMEPROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 290, Page 13128-13143, Year 2015 |
Publish date | Feb 16, 2015 (structure data deposition date) |
![]() | Pallan, P.S. / Wang, C. / Lei, L. / Yoshimoto, F.K. / Auchus, R.J. / Waterman, M.R. / Guengerich, F.P. / Egli, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.64 Å |
Structure data | ![]() PDB-4y8w: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HEM: ![]() ChemComp-STR: ![]() ChemComp-HOH: |
Source |
|
![]() | OXIDOREDUCTASE / steroid hydroxylation / monooxygenases / adrenal steroidogenesis / congenital adrenal hyperplasia / Addison's disease / kinetic isotope effects |