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TitleCrystal Structure of the N-Acetylmuramic Acid alpha-1-Phosphate (MurNAc-alpha 1-P) Uridylyltransferase MurU, a Minimal Sugar Nucleotidyltransferase and Potential Drug Target Enzyme in Gram-negative Pathogens.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 10804-10813, Year 2015
Publish dateFeb 16, 2015 (structure data deposition date)
AuthorsRenner-Schneck, M. / Hinderberger, I. / Gisin, J. / Exner, T. / Mayer, C. / Stehle, T.
External linksJ. Biol. Chem. / PubMed:25767118
MethodsX-ray diffraction
Resolution1.7 - 1.8 Å
Structure data

PDB-4y7t:
Structural analysis of MurU
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4y7u:
Structural analysis of MurU
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4y7v:
Structural analysis of MurU
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-2KH:
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine

ChemComp-491:
2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-1-O-phosphono-alpha-D-glucopyranose

ChemComp-2PN:
IMIDODIPHOSPHORIC ACID

Source
  • pseudomonas putida (bacteria)
  • pseudomonas putida (strain bird-1) (bacteria)
KeywordsTRANSFERASE / Nucleotidyltransferase family protein / uridyltransferase / Rossman fold / MurNAc-1P

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