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-Structure paper
Title | Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation. |
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Journal, issue, pages | Biochemistry, Vol. 54, Page 3037-3050, Year 2015 |
Publish date | Feb 13, 2015 (structure data deposition date) |
Authors | Feldman, J.L. / Dittenhafer-Reed, K.E. / Kudo, N. / Thelen, J.N. / Ito, A. / Yoshida, M. / Denu, J.M. |
External links | Biochemistry / PubMed:25897714 |
Methods | X-ray diffraction |
Resolution | 1.6 - 1.9 Å |
Structure data | PDB-4y6l: PDB-4y6o: PDB-4y6q: |
Chemicals | ChemComp-ZN: ChemComp-HOH: ChemComp-OMR: |
Source |
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Keywords | HYDROLASE/PEPTIDE / sirtuin / SIRT / NAD-dependent deacetylase / myristoylated lysine / HYDROLASE-PEPTIDE complex / HYDROLASE / 2-O-myristoyl-ADP-ribose / acyl-ADP-ribose / complex / deacylase / intermediate |