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Structure paper

TitleMolecular basis of ion permeability in a voltage-gated sodium channel.
Journal, issue, pagesEmbo J., Vol. 35, Page 820-830, Year 2016
Publish dateDec 10, 2014 (structure data deposition date)
AuthorsNaylor, C.E. / Bagneris, C. / DeCaen, P.G. / Sula, A. / Scaglione, A. / Clapham, D.E. / Wallace, B.A.
External linksEmbo J. / PubMed:26873592
MethodsX-ray diffraction
Resolution2.62 - 3.5 Å
Structure data

PDB-4x88:
E178D Selectivity filter mutant of NavMS voltage-gated pore
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-4x89:
NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

PDB-4x8a:
NavMS pore and C-terminal domain grown from protein purified in LiCl
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

PDB-5bzb:
NavMs voltage-gated sodium channel pore and C-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-2CV:
HEGA-10 / detergent*YM

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-AG:
SILVER ION

ChemComp-2PE:
NONAETHYLENE GLYCOL / precipitant*YM

ChemComp-12P:
DODECAETHYLENE GLYCOL / precipitant*YM

Source
  • magnetococcus marinus mc-1 (bacteria)
  • magnetococcus sp. (strain mc-1) (bacteria)
KeywordsTRANSPORT PROTEIN / SELECTIVITY FILTER / MEMBRANE PROTEIN

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