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Structure paper

TitleNanobody binding to a conserved epitope promotes norovirus particle disassembly.
Journal, issue, pagesJ. Virol., Vol. 89, Page 2718-2730, Year 2015
Publish dateDec 9, 2014 (structure data deposition date)
AuthorsKoromyslova, A.D. / Hansman, G.S.
External linksJ. Virol. / PubMed:25520510
MethodsX-ray diffraction
Resolution1.7 - 2.15 Å
Structure data

PDB-4x7c:
Crystal structure of Saga-2006 GII.4 P domain in complex with Nano-85
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4x7d:
Crystal structure of 2012 NSW GII.4 P domain in complex with Nano-85
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-4x7e:
Crystal structure of norovirus GII.10 P domain in complex with Nano-85
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

PDB-4x7f:
Crystal structure of norovirus GII.10 P domain in complex with Nano-25
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-NA:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-IMD:
IMIDAZOLE

Source
  • norovirus hu/gii-4/saga1/2006/jp
  • vicugna pacos (alpaca)
  • norovirus hu/gii.4/sydney/nsw0514/2012/au
  • lama glama (llama)
  • norovirus
  • norwalk virus
KeywordsVIRAL PROTEIN / Nanobody / VHH domain / Norovirus / Protruding domain

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