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Structure paper

TitleReorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 9716-9721, Year 2013
Publish dateDec 20, 2011 (structure data deposition date)
AuthorsFagan, C.E. / Dunkle, J.A. / Maehigashi, T. / Dang, M.N. / Devaraj, A. / Miles, S.J. / Qin, D. / Fredrick, K. / Dunham, C.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:23630274
MethodsX-ray diffraction
Resolution3.516 - 3.9 Å
Structure data

PDB-4v8j:
Crystal structure of the bacterial ribosome ram mutation G347U.
Method: X-RAY DIFFRACTION / Resolution: 3.9 Å

PDB-4v97:
Crystal structure of the bacterial ribosome ram mutation G299A.
Method: X-RAY DIFFRACTION / Resolution: 3.516 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

ChemComp-ZN:
Unknown entry

Source
  • thermus thermophilus (bacteria)
  • escherichia coli (E. coli)
KeywordsRIBOSOME / Protein biosynthesis / ribosomes / RNA / tRNA / transfer / ribosomal ambiguity mutations / ram / 30S / 70S / 16S / ribosomal subunit / PAROMOMYCIN as crystallization agent / ribosomal ambiguity mutation

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